Across TCGA patient cohorts, BCR protein abundance is significantly associated with the RNA expression of many other genes, with 9,719 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCR-associated genes across cancer lineages are MAPK1, UBE2L3, and FBXW4P1. Each is linked with BCR in more than 6 cancer types. Because this analysis shows association rather than direction, both BCR-to-partner and partner-to-BCR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCR→partner) and Y-score (partner→BCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAPK1 →	+0.634	+0.327	.001	<.001	3	7
OV	UBE2L3 →	+0.477	+0.331	.004	<.001	3	7
GBM	FBXW4P1 →	+0.727	+0.384	<.001	<.001	3	7
GBM	SNRPD3 →	+0.607	+0.482	<.001	<.001	3	5
UCEC	BCRP8 →	+0.731	+0.215	.004	<.001	3	5
GBM	RN7SL263P →	+0.599	+0.295	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,719 associations by consensus.

Exploration

BCR survival (RNA) · tumor vs normal (RNA) · all BCR data types