Across TCGA cell cohorts, BCR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,116 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BCR-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Positive regulation of protein import into nucleus. Each is linked with BCR in more than 14 cancer types. Because this analysis shows association rather than direction, both BCR-to-partner and partner-to-BCR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCR→partner) and Y-score (partner→BCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Symbiont-mediated disruption of host cellular anatomical structure →	+0.142	+1.233	.001	<.001	3	15
LIVER	Symbiont-mediated disruption of host anatomical structure →	+0.142	+1.233	.001	<.001	3	15
LIVER	Positive regulation of protein import into nucleus →	+0.114	+1.267	.009	.003	2	15
UPPER_AERODIGESTIVE_TRACT	Interleukin-34-mediated signaling pathway →	+0.188	+0.942	.003	.001	3	14
BREAST	Regulation of protein localization to nucleus →	+0.080	+0.997	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of chromosome condensation →	+0.168	+1.005	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,116 associations by consensus.

Exploration

BCR survival (RNA) · tumor vs normal (RNA) · all BCR data types