Across TCGA patient cohorts, BCOR protein abundance is significantly associated with the RNA expression of many other genes, with 3,601 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCOR-associated genes across cancer lineages are DPH6, KCNK12, and RNA5SP450. Each is linked with BCOR in more than 2 cancer types. Because this analysis shows association rather than direction, both BCOR-to-partner and partner-to-BCOR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCOR→partner) and Y-score (partner→BCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DPH6 →	+0.559	+0.231	<.001	.003	3	3
CCRCC	KCNK12 →	+0.383	+0.344	.004	.002	3	2
OV	RNA5SP450 →	+0.794	+0.567	.009	.001	3	2
BRCA	MET →	-0.957	-0.271	.001	.002	3	2
CCRCC	DICER1 →	+0.413	+0.398	.002	.009	3	2
CCRCC	PPP4R3A →	+0.450	+0.425	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,601 associations by consensus.

Exploration

BCOR survival (RNA) · tumor vs normal (RNA) · all BCOR data types