Across TCGA cell cohorts, BCO2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCO2-associated genes across cancer lineages are KCNG4, PRLHR, and CLEC4F. Each is linked with BCO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCO2-to-partner and partner-to-BCO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCO2→partner) and Y-score (partner→BCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KCNG4 →	+0.006	+5.539	.001	.003	3	1
BLOOD_Lymphoma	PRLHR →	+0.010	+5.247	<.001	.001	3	1
LARGE_INTESTINE	CLEC4F →	+0.199	+3.974	.005	.002	3	1
LARGE_INTESTINE	GALNTL6 →	+0.177	+3.794	.001	.001	3	1
LARGE_INTESTINE	OR4F4 →	+0.019	+3.103	<.001	.004	3	1
LARGE_INTESTINE	KCNIP1 →	+0.058	+3.472	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

BCO2 survival (RNA) · tumor vs normal (RNA) · all BCO2 data types