BCL7C

Across TCGA cell cohorts, BCL7C mutation is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCL7C-associated genes across cancer lineages are TAS2R39, IDI2, and ASB17. Each is linked with BCL7C in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL7C-to-partner and partner-to-BCL7C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R39 grouped by BCL7C-low versus BCL7C-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL7C→partner) and Y-score (partner→BCL7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TAS2R39 →	+0.051	+4.339	<.001	.002	3	2
OVARY	IDI2 →	+0.021	+4.029	.001	.009	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1
OVARY	OR2AK2 →	+0.060	+4.029	<.001	.009	3	1
CNS	PRAMEF10 →	+0.386	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

TAS2R39 by BCL7C expression — BLOOD_Leukemia

Explore this box plot interactively →