BCL11A

Across TCGA patient cohorts, BCL11A protein abundance is significantly associated with the RNA expression of many other genes, with 14,028 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL11A-associated genes across cancer lineages are SEPTIN3, OCA2, and POP1. Each is linked with BCL11A in more than 2 cancer types. Because this analysis shows association rather than direction, both BCL11A-to-partner and partner-to-BCL11A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL11A versus SEPTIN3 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL11A→partner) and Y-score (partner→BCL11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN3 →	+1.272	+1.096	.006	.001	3	3
LSCC	OCA2 →	+1.160	+0.589	<.001	<.001	3	3
BRCA	POP1 →	+0.487	+0.878	<.001	<.001	3	3
GBM	TUBB4A →	+0.973	+0.539	.003	<.001	3	3
GBM	DLX5 →	+1.539	+0.761	.002	.001	3	3
BRCA	TRIM2 →	+0.973	+1.010	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,028 associations by consensus.

BCL11A vs SEPTIN3 — BRCA

Explore this scatter interactively →