BCDIN3D

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCDIN3D mutation is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCDIN3D-associated genes across cancer lineages are VN1R90P, RNU6-1226P, and YBX1P7. Each is linked with BCDIN3D in more than 1 cancer types. Because this analysis shows association rather than direction, both BCDIN3D-to-partner and partner-to-BCDIN3D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCDIN3D→partner) and Y-score (partner→BCDIN3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAVN1R90P →+0.064+3.130.006.00732
KIRPRNU6-1226P →+0.370+5.159<.001.00732
KIRPYBX1P7 →+0.091+5.060<.001.00832
UCECARPP19P1 →+0.144+3.155.004.00132
UCECRNA5SP418 →+0.559+2.600.008.00532
UCECYAF2 →+0.461+3.332.004.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

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