Across TCGA pan-cancer cohorts, BCDIN3D RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated BCDIN3D data layer compared with 3 for mutation status and 3 for mass-spec protein.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BCDIN3D RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated BCDIN3D expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCEC show a favorable association.
KIRC, UCEC, and UVM are the cancer types where BCDIN3D RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.