BAHD1

Across TCGA cell cohorts, BAHD1 mutation is significantly associated with the mutation status of many other genes, with 5,574 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BAHD1-associated genes across cancer lineages are FILIP1, WDR33, and SPEN. Each is linked with BAHD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BAHD1-to-partner and partner-to-BAHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FILIP1 grouped by BAHD1-low versus BAHD1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAHD1→partner) and Y-score (partner→BAHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FILIP1 →	+2.473	+3.139	.002	.002	1	5
BLOOD_Lymphoma	WDR33 →	+3.832	+4.316	.002	.002	1	5
LARGE_INTESTINE	SPEN →	+1.552	+3.495	.005	.005	1	5
BLOOD_Leukemia	SORBS1 →	+4.894	+5.870	<.001	<.001	1	5
BLOOD_Leukemia	CARD11 →	+2.779	+4.326	.006	.006	1	5
LARGE_INTESTINE	SOGA3 →	+1.799	+3.769	.002	.002	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,574 associations by consensus.

FILIP1 by BAHD1 expression — SKIN

Explore this box plot interactively →