BAALC

Across TCGA patient cohorts, BAALC mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BAALC-associated genes across cancer lineages are PDCD4 and TFRC. Each is linked with BAALC in more than 1 cancer types. Because this analysis shows association rather than direction, both BAALC-to-partner and partner-to-BAALC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by BAALC-low versus BAALC-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BAALC→partner) and Y-score (partner→BAALC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.934	-2.990	<.001	.036	3	1
UCEC	TFRC →	+0.728	+3.169	.012	.020	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PDCD4 by BAALC expression — UCEC

Explore this box plot interactively →