BAALC

Across TCGA pan-cancer cohorts, BAALC RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated BAALC data layer compared with 3 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher BAALC RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BAALC expression acts as an unfavorable survival marker, although some lineages such as SKCM and LGG show a favorable association.

BLCA, UVM, and UCS are the cancer types where BAALC RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	IV	0.098	0.329	<.001	97	view →
UVM	DFS	Quartile	II,III,IV	0.251	0.729	<.001	91	view →
UCS	DFS	Tertile	III,IV	0.265	0.578	.017	56	view →
SKCM	DFS	Quartile	II,III,IV	0.339	0.142	<.001	48	view →
LGG	DFS	Quartile	All	0.852	0.691	<.001	24	view →
THCA	DFS	Tertile	III,IV	0.941	0.552	.010	23	view →
KIRP	DFS	Quartile	II,III,IV	0.254	0.940	.008	22	view →
STAD	OS	Quartile	All	0.358	0.551	.004	21	view →
HNSC	OS	Tertile	All	0.607	0.804	.020	12	view →
SCLC	DFS	Median	IV	0.651	0.148	.006	12	view →
LIHC	DFS	Tertile	III,IV	0.477	0.242	.006	12	view →
PRAD	DFS	Tertile	All	0.967	0.883	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

BAALC–BLCA (DFS)

Open the BLCA breakdown →