BAALC

Across TCGA pan-cancer cohorts, BAALC RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of BAALC’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where BAALC RNA is repressed in tumor relative to normal tissue. In most cancer types BAALC is over-expressed in tumor, although a few such as COAD and KIRP show the opposite, repressed pattern.

COAD, KIRP, and HNSC are the cancer types where BAALC tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BAALC RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.976	<.001	11	view →
KIRP	Male	II,III,IV	−0.907	<.001	10	view →
HNSC	All	III,IV	+0.749	<.001	9	view →
LUAD	Female	III,IV	−2.418	<.001	8	view →
KICH	Female	II,III,IV	+3.321	<.001	7	view →
UCEC	All	All	−1.183	<.001	6	view →
THCA	All	All	−0.607	<.001	6	view →
BRCA	All	All	−1.040	<.001	4	view →
STAD	Male	III,IV	−0.916	.003	4	view →
LUSC	Female	III,IV	−2.175	.003	3	view →
READ	Female	All	−1.596	<.001	2	view →
PAAD	Female	All	−1.595	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

BAALC–COAD

Open the COAD breakdown →