BAALC

Across TCGA cell cohorts, BAALC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,470 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BAALC-associated GO terms across cancer lineages are Positive regulation of cytoplasmic translation, Regulation of tumor necrosis factor-mediated signaling pathway, and Golgi vesicle transport. Each is linked with BAALC in more than 7 cancer types. Because this analysis shows association rather than direction, both BAALC-to-partner and partner-to-BAALC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic translation grouped by BAALC-low versus BAALC-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BAALC→partner) and Y-score (partner→BAALC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of cytoplasmic translation →	+0.154	+0.297	<.001	.001	3	8
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.053	+0.210	.006	.008	2	8
STOMACH	Golgi vesicle transport →	+0.085	+0.273	<.001	.004	3	7
LUNG_SCLC	Regulation of myoblast fusion →	+0.104	+2.790	<.001	<.001	3	7
SKIN	Negative regulation of myoblast fusion →	+0.078	+2.069	<.001	.001	3	7
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+2.828	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,470 associations by consensus.

Positive regulation of cytoplasmic translation by BAALC expression — STOMACH

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