B4GALT3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B4GALT3 mutation is significantly associated with the RNA expression of many other genes, with 4,007 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALT3-associated genes across cancer lineages are RN7SL248P, RNU6-1242P, and RN7SKP221. Each is linked with B4GALT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT3-to-partner and partner-to-B4GALT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by B4GALT3-low versus B4GALT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT3→partner) and Y-score (partner→B4GALT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.046+2.783<.001.00932
COADRNU6-1242P →+1.096+5.017<.001.00932
BRCARN7SKP221 →+0.065+7.471<.001.00832
UCECRNA5SP251 →+0.400+2.481<.001.00232
UCECSDCBPP3 →+0.180+2.145.003<.00132
UCECLINC01072 →+0.114+2.048<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,007 associations by consensus.

RN7SL248P by B4GALT3 expression — UCEC

Box plot of RN7SL248P in B4GALT3-low vs B4GALT3-high samples in UCEC.

Explore this box plot interactively →

Exploration