B4GALNT4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B4GALNT4 mutation is significantly associated with the RNA expression of many other genes, with 1,191 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT4-associated genes across cancer lineages are LSM12, PTTG1, and GH2. Each is linked with B4GALNT4 in more than 2 cancer types. Because this analysis shows association rather than direction, both B4GALNT4-to-partner and partner-to-B4GALNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM12 grouped by B4GALNT4-low versus B4GALNT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT4→partner) and Y-score (partner→B4GALNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLSM12 →+0.470+2.362.002.00333
SKCMPTTG1 →+0.464+2.254.008.00133
LUADGH2 →+0.495+3.914.005.00432
SKCMOR5J7P →+0.025+3.256<.001.00332
SKCMHAUS8P1 →+0.010+4.424<.001.00232
SKCMNFKBIB →+0.329+3.347.003.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,191 associations by consensus.

LSM12 by B4GALNT4 expression — UCEC

Box plot of LSM12 in B4GALNT4-low vs B4GALNT4-high samples in UCEC.

Explore this box plot interactively →

Exploration