B4GALNT4

Across TCGA pan-cancer cohorts, B4GALNT4 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of B4GALNT4’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where B4GALNT4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types B4GALNT4 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

LUAD, COAD, and BLCA are the cancer types where B4GALNT4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in B4GALNT4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	All	+2.035	<.001	11	view →
COAD	Male	IV	+3.386	<.001	10	view →
BLCA	All	All	+2.029	<.001	10	view →
KIRC	All	III,IV	+0.616	<.001	9	view →
LUSC	Female	All	+4.042	<.001	7	view →
BRCA	All	III,IV	+1.325	<.001	6	view →
CHOL	Female	All	+5.236	<.001	5	view →
HNSC	Male	All	+1.251	<.001	5	view →
LIHC	All	All	+0.466	.009	3	view →
READ	All	III,IV	+2.740	.002	2	view →
PRAD	All	All	+1.106	<.001	2	view →
KICH	Female	All	−0.538	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

B4GALNT4–LUAD

Open the LUAD breakdown →