B4GALNT4

Across TCGA patient cohorts, B4GALNT4 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT4-associated genes across cancer lineages are mTOR_pS2448, YAP, and eEF2. Each is linked with B4GALNT4 in more than 2 cancer types. Because this analysis shows association rather than direction, both B4GALNT4-to-partner and partner-to-B4GALNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by B4GALNT4-low versus B4GALNT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT4→partner) and Y-score (partner→B4GALNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.133	-1.986	.013	.029	3	3
SKCM	YAP →	+0.197	+2.824	.026	.034	3	2
UCEC	eEF2 →	+0.322	+1.584	.012	.019	3	2
UCEC	EGFR_pY1068 →	-0.203	-1.925	.024	.005	3	2
UCEC	ERK2 →	+0.236	+3.000	<.001	<.001	3	2
UCEC	Rad50 →	-0.233	-1.925	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

mTOR_pS2448 by B4GALNT4 expression — UCEC

Explore this box plot interactively →