B3GNT7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, B3GNT7 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible B3GNT7-associated genes across cancer lineages are SEL1L2, TAS2R7, and TLE7. Each is linked with B3GNT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT7-to-partner and partner-to-B3GNT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEL1L2 grouped by B3GNT7-low versus B3GNT7-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT7→partner) and Y-score (partner→B3GNT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaSEL1L2 →+0.015+5.643<.001.00231
BLOOD_LymphomaTAS2R7 →+0.029+5.643<.001.00231
BLOOD_LymphomaTLE7 →+0.016+5.643<.001.00231
LUNG_SCLCDUXA →+0.039+4.523.007.00331
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SEL1L2 by B3GNT7 expression — BLOOD_Lymphoma

Box plot of SEL1L2 in B3GNT7-low vs B3GNT7-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration