B3GNT7

Across TCGA pan-cancer cohorts, B3GNT7 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of B3GNT7’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where B3GNT7 RNA is repressed in tumor relative to normal tissue. In most cancer types B3GNT7 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, THCA, and KICH are the cancer types where B3GNT7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in B3GNT7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	−2.914	<.001	11	view →
THCA	Female	II,III,IV	+2.135	<.001	11	view →
KICH	Male	II,III,IV	−1.510	<.001	11	view →
LUSC	Female	II,III,IV	−3.384	<.001	7	view →
LUAD	Male	All	−1.177	<.001	6	view →
KIRC	All	III,IV	−0.541	<.001	6	view →
CHOL	All	All	+3.771	<.001	5	view →
STAD	Male	All	+1.545	.010	4	view →
READ	All	All	−3.791	.001	3	view →
ESCA	All	All	+1.997	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

B3GNT7–COAD

Open the COAD breakdown →