B3GNT4

Across TCGA patient cohorts, B3GNT4 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNT4-associated genes across cancer lineages are Caspase-7-cleavedD198, eEF2, and eIF4E. Each is linked with B3GNT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT4-to-partner and partner-to-B3GNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by B3GNT4-low versus B3GNT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT4→partner) and Y-score (partner→B3GNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.865	+1.604	<.001	.041	3	2
UCEC	eEF2 →	+0.343	+3.169	.014	.018	3	1
UCEC	eIF4E →	+0.185	+3.183	.025	.009	3	1
UCEC	A-Raf_pS299 →	-0.124	-3.321	.008	.010	3	1
UCEC	GAPDH →	+0.415	+2.000	.048	.010	3	1
UCEC	JNK2 →	+0.218	+2.834	.005	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Caspase-7-cleavedD198 by B3GNT4 expression — UCEC

Explore this box plot interactively →