B3GNT4

Across TCGA cell cohorts, B3GNT4 mutation is significantly associated with the drug of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B3GNT4-associated genes across cancer lineages are Niraparib, AZD5438, and GSK2801. Each is linked with B3GNT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT4-to-partner and partner-to-B3GNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Niraparib grouped by B3GNT4-low versus B3GNT4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT4→partner) and Y-score (partner→B3GNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Niraparib →	+0.479	+2.646	.006	.047	3	1
LARGE_INTESTINE	AZD5438 →	+0.498	+2.777	.043	.038	3	1
LARGE_INTESTINE	GSK2801 →	+0.333	+2.649	.036	.046	3	1
LARGE_INTESTINE	Masitinib →	+0.499	+2.652	.020	.045	3	1
LARGE_INTESTINE	PRIMA-1MET →	+0.654	+2.646	.014	.047	2	1
LARGE_INTESTINE	SGC-CBP30 →	+0.322	+2.649	.022	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Niraparib by B3GNT4 expression — LARGE_INTESTINE

Explore this box plot interactively →