B3GNT3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GNT3 mutation is significantly associated with the RNA expression of many other genes, with 452 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible B3GNT3-associated genes across cancer lineages are LONRF2P1, COPS8P1, and SNORD31B. Each is linked with B3GNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT3-to-partner and partner-to-B3GNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LONRF2P1 grouped by B3GNT3-low versus B3GNT3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT3→partner) and Y-score (partner→B3GNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLONRF2P1 →+0.096+5.812<.001.00332
LUADCOPS8P1 →+0.127+5.481<.001.00532
LUADSNORD31B →+0.784+5.712<.001.00332
UCECGABRE →-0.883-3.584.004.00332
SKCMRNA5SP531 →+0.063+4.141<.001.00432
UCECUBXN6 →+0.424+3.217.008.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 452 associations by consensus.

LONRF2P1 by B3GNT3 expression — CESC

Box plot of LONRF2P1 in B3GNT3-low vs B3GNT3-high samples in CESC.

Explore this box plot interactively →

Exploration