B3GALNT2

Across TCGA patient cohorts, B3GALNT2 mutation is significantly associated with the RNA expression of many other genes, with 3,046 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALNT2-associated genes across cancer lineages are HLA-Z, RNA5SP405, and RNU6-1228P. Each is linked with B3GALNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALNT2-to-partner and partner-to-B3GALNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HLA-Z grouped by B3GALNT2-low versus B3GALNT2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALNT2→partner) and Y-score (partner→B3GALNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	HLA-Z →	+1.066	+3.685	<.001	.007	3	2
UCEC	RNA5SP405 →	+0.236	+3.494	<.001	<.001	3	2
COAD	RNU6-1228P →	+0.468	+6.409	<.001	<.001	3	2
UCEC	CBX1P2 →	+0.242	+2.103	.007	.009	3	2
UCEC	LINC02438 →	+0.523	+2.831	.001	.001	3	2
BLCA	USP9YP2 →	+0.039	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,046 associations by consensus.

HLA-Z by B3GALNT2 expression — SKCM

Explore this box plot interactively →