B2M

Across TCGA patient cohorts, B2M RNA expression is significantly associated with the protein abundance of many other proteins, with 14,731 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible B2M-associated proteins across cancer lineages are TAP1, TAPBP, and UBE2L6. Each is linked with B2M in more than 9 cancer types. Because this analysis shows association rather than direction, both B2M-to-partner and partner-to-B2M results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, B2M versus TAP1 in OV, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (B2M→partner) and Y-score (partner→B2M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TAP1 →	+0.717	+1.025	<.001	<.001	3	10
HNSC	TAPBP →	+0.774	+1.296	<.001	<.001	3	10
LSCC	UBE2L6 →	+0.596	+0.684	<.001	<.001	3	10
OV	APOL2 →	+0.733	+0.862	<.001	<.001	3	10
HNSC	APOL3 →	+0.921	+0.770	<.001	.006	3	10
GBM	OAS2 →	+0.852	+0.601	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,731 associations by consensus.

B2M vs TAP1 — OV

Explore this scatter interactively →