AZIN2

Across TCGA patient cohorts, AZIN2 mutation is significantly associated with the RNA expression of many other genes, with 2,167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AZIN2-associated genes across cancer lineages are RNU1-17P, UBE2V1P4, and YBX1P9. Each is linked with AZIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AZIN2-to-partner and partner-to-AZIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by AZIN2-low versus AZIN2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZIN2→partner) and Y-score (partner→AZIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.395	+5.103	<.001	.008	3	2
CESC	UBE2V1P4 →	+0.127	+5.103	<.001	.008	3	2
CESC	YBX1P9 →	+0.070	+5.010	<.001	.009	3	2
UCEC	RN7SL248P →	+0.060	+3.137	<.001	<.001	3	2
SKCM	RNA5SP225 →	+0.076	+4.488	<.001	.003	3	2
SKCM	SRIP2 →	+0.123	+3.095	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,167 associations by consensus.

RNU1-17P by AZIN2 expression — CESC

Explore this box plot interactively →