AZIN2

Across TCGA pan-cancer cohorts, AZIN2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated AZIN2 data layer compared with 6 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher AZIN2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated AZIN2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, SKCM, and BRCA are the cancer types where AZIN2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.875	0.695	<.001	103	view →
SKCM	OS	Median	II,III,IV	0.392	0.226	.005	35	view →
BRCA	OS	Median	III,IV	0.625	0.467	.004	29	view →
DLBC	DFS	Quartile	II,III,IV	1.000	0.565	.020	28	view →
OV	OS	Quartile	II,III,IV	0.316	0.444	.003	24	view →
CHOL	DFS	Quartile	II,III,IV	0.796	0.139	.022	21	view →
ESCA	DFS	Median	III,IV	0.610	0.311	<.001	19	view →
PRAD	DFS	Quartile	All	0.704	0.878	<.001	18	view →
LIHC	DFS	Tertile	All	0.367	0.564	.013	12	view →
KIRP	DFS	Quartile	IV	0.308	0.733	.038	12	view →
HNSC	DFS	Tertile	III,IV	0.422	0.263	.017	11	view →
SCLC	OS	Median	All	0.928	0.531	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

AZIN2–LUAD (OS)

Open the LUAD breakdown →