AVPR1A

Across TCGA patient cohorts, AVPR1A mutation is significantly associated with the RNA expression of many other genes, with 1,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AVPR1A-associated genes across cancer lineages are TACC3, SEC16A, and CEP295. Each is linked with AVPR1A in more than 2 cancer types. Because this analysis shows association rather than direction, both AVPR1A-to-partner and partner-to-AVPR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TACC3 grouped by AVPR1A-low versus AVPR1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPR1A→partner) and Y-score (partner→AVPR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TACC3 →	+0.523	+2.815	.007	.001	3	3
UCEC	SEC16A →	+0.592	+2.010	<.001	.001	3	3
COAD	CEP295 →	+0.648	+3.513	.001	.002	3	3
COAD	SCG5-AS1 →	+0.230	+3.031	<.001	.001	3	3
UCEC	SFXN1 →	+0.426	+2.880	.001	.001	3	3
UCEC	WDR62 →	+0.620	+4.021	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,514 associations by consensus.

TACC3 by AVPR1A expression — UCEC

Explore this box plot interactively →