AVPR1A

Across TCGA pan-cancer cohorts, AVPR1A RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of AVPR1A’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where AVPR1A RNA is repressed in tumor relative to normal tissue. In most cancer types AVPR1A is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LIHC are the cancer types where AVPR1A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AVPR1A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	−3.730	<.001	11	view →
KIRC	All	III,IV	−1.115	<.001	10	view →
LIHC	Female	II,III,IV	−3.137	<.001	9	view →
KIRP	Female	All	−2.748	<.001	9	view →
UCEC	All	All	−2.769	<.001	6	view →
BRCA	All	All	−0.983	<.001	6	view →
HNSC	Female	All	+0.793	.003	6	view →
KICH	All	All	+2.085	<.001	5	view →
CHOL	All	All	−3.155	<.001	3	view →
LUAD	Male	III,IV	+0.695	.015	3	view →
BLCA	Female	All	−1.006	.049	2	view →
READ	Female	All	−0.904	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

AVPR1A–THCA

Open the THCA breakdown →