AVPR1A

Across TCGA pan-cancer cohorts, AVPR1A RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated AVPR1A data layer compared with 7 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher AVPR1A RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AVPR1A expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRP, BLCA, and UVM are the cancer types where AVPR1A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	All	0.826	0.956	.001	81	view →
BLCA	DFS	Median	II,III,IV	0.438	0.572	.001	63	view →
UVM	DFS	Tertile	III,IV	0.319	0.757	.002	59	view →
MESO	OS	Quartile	II,III,IV	0.277	0.558	.002	43	view →
KIRC	DFS	Tertile	All	0.910	0.827	.001	42	view →
STAD	DFS	Quartile	All	0.498	0.673	.004	38	view →
HNSC	DFS	Median	All	0.421	0.287	.006	34	view →
THCA	OS	Tertile	IV	0.747	0.973	.025	20	view →
COAD	DFS	Tertile	III,IV	0.589	0.751	.017	14	view →
THYM	DFS	Median	All	0.964	0.649	.004	13	view →
ACC	OS	Tertile	IV	0.219	0.850	.024	12	view →
LIHC	OS	Tertile	III,IV	0.835	0.470	.011	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

AVPR1A–KIRP (DFS)

Open the KIRP breakdown →