AVPR1A

Across TCGA cell cohorts, AVPR1A mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible AVPR1A-associated genes across cancer lineages are OR2L8, UTF1, and FAM24A. Each is linked with AVPR1A in more than 1 cancer types. Because this analysis shows association rather than direction, both AVPR1A-to-partner and partner-to-AVPR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L8 grouped by AVPR1A-low versus AVPR1A-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPR1A→partner) and Y-score (partner→AVPR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2L8 →	+0.012	+4.681	<.001	.003	3	2
LARGE_INTESTINE	UTF1 →	+0.015	+3.217	<.001	.006	3	1
LARGE_INTESTINE	FAM24A →	+0.035	+3.700	<.001	.009	3	1
LARGE_INTESTINE	PRR23A →	+0.031	+3.217	<.001	.006	3	1
STOMACH	SSX7 →	+0.433	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	GALNTL5 →	+0.056	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

OR2L8 by AVPR1A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →