AVPI1

Across TCGA patient cohorts, AVPI1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AVPI1-associated genes across cancer lineages are RN7SL248P, MIR5708, and SNRPCP20. Each is linked with AVPI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AVPI1-to-partner and partner-to-AVPI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by AVPI1-low versus AVPI1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPI1→partner) and Y-score (partner→AVPI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.118	+4.400	<.001	.006	3	2
UCEC	MIR5708 →	+0.359	+4.555	<.001	.005	3	1
UCEC	SNRPCP20 →	+0.366	+3.463	<.001	.003	3	1
UCEC	RNU6-1331P →	+0.363	+3.666	.005	.004	3	1
UCEC	RNU6-188P →	+0.501	+4.092	.001	<.001	3	1
UCEC	RNU6-484P →	+1.052	+3.488	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

RN7SL248P by AVPI1 expression — UCEC

Explore this box plot interactively →