AVP

Across TCGA cell cohorts, AVP RNA expression is significantly associated with the mutation status of many other genes, with 485 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AVP-associated genes across cancer lineages are DSE, C8A, and TSC2. Each is linked with AVP in more than 2 cancer types. Because this analysis shows association rather than direction, both AVP-to-partner and partner-to-AVP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DSE grouped by AVP-low versus AVP-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVP→partner) and Y-score (partner→AVP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DSE →	+3.855	+1.335	.007	.009	3	3
BLOOD_Lymphoma	C8A →	+4.794	+0.031	<.001	<.001	3	3
SOFT_TISSUE	TSC2 →	+3.977	+0.065	.007	<.001	3	2
SOFT_TISSUE	PAPPA2 →	+3.977	+0.065	.007	<.001	3	2
SOFT_TISSUE	ZC3H4 →	+4.977	+0.097	.002	<.001	3	2
SOFT_TISSUE	CCDC88C →	+4.392	+0.078	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 485 associations by consensus.

DSE by AVP expression — BLOOD_Leukemia

Explore this box plot interactively →