AVP

Across TCGA pan-cancer cohorts, AVP RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated AVP data layer compared with 2 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher AVP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AVP expression acts as an unfavorable survival marker, although some lineages such as CESC and LUAD show a favorable association.

STAD, COAD, and UCS are the cancer types where AVP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.432	0.616	.002	63	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	39	view →
UCS	DFS	Median	IV	0.367	0.952	.001	36	view →
CESC	OS	Tertile	III,IV	0.855	0.279	.010	36	view →
LUAD	DFS	Tertile	II,III,IV	0.660	0.208	.006	35	view →
KIRC	OS	Quartile	All	0.815	0.890	.007	27	view →
DLBC	OS	Tertile	II,III,IV	0.323	0.920	.026	15	view →
BRCA	OS	Tertile	III,IV	0.977	0.887	.015	12	view →
SARC	OS	Tertile	All	0.601	0.764	.013	12	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →
KIRP	OS	Median	All	0.950	0.848	.010	9	view →
BLCA	OS	Median	II,III,IV	0.512	0.366	.023	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

AVP–STAD (DFS)

Open the STAD breakdown →