AURKC

Across TCGA patient cohorts, AURKC protein abundance is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AURKC-associated genes across cancer lineages are SEZ6L, NEFH, and CRYGD. Each is linked with AURKC in more than 1 cancer types. Because this analysis shows association rather than direction, both AURKC-to-partner and partner-to-AURKC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AURKC versus SEZ6L in LSCC, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AURKC→partner) and Y-score (partner→AURKC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEZ6L →	+0.871	+0.308	.007	.007	2	1
LSCC	NEFH →	+4.420	+0.308	.001	.007	2	1
LSCC	CRYGD →	+0.330	+0.308	.005	.007	2	1
LSCC	AREL1 →	+1.134	+0.308	.006	.007	2	1
LSCC	CRHR1 →	+0.155	+0.308	<.001	.007	2	1
LSCC	LRAT →	+1.358	+0.308	.002	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

AURKC vs SEZ6L — LSCC

Explore this scatter interactively →