ATXN7L3

Across TCGA cell cohorts, ATXN7L3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATXN7L3-associated genes across cancer lineages are AVP and REG3G. Each is linked with ATXN7L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATXN7L3-to-partner and partner-to-ATXN7L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ATXN7L3-low versus ATXN7L3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN7L3→partner) and Y-score (partner→ATXN7L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	REG3G →	+0.026	+4.867	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

AVP by ATXN7L3 expression — BLOOD_Lymphoma

Explore this box plot interactively →