ATXN3L

Across TCGA patient cohorts, ATXN3L mutation is significantly associated with the RNA expression of many other genes, with 2,562 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATXN3L-associated genes across cancer lineages are RN7SL83P, EDDM3DP, and MIR4314. Each is linked with ATXN3L in more than 2 cancer types. Because this analysis shows association rather than direction, both ATXN3L-to-partner and partner-to-ATXN3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL83P grouped by ATXN3L-low versus ATXN3L-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN3L→partner) and Y-score (partner→ATXN3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RN7SL83P →	+0.181	+5.345	<.001	.005	3	3
COAD	EDDM3DP →	+0.104	+4.435	.001	.001	3	2
COAD	MIR4314 →	+0.293	+4.917	<.001	.003	3	2
SKCM	ANKRD33B-AS1 →	+0.045	+3.069	<.001	.009	3	2
UCEC	FCER1A →	-0.853	-2.523	<.001	<.001	3	2
UCEC	CA5BP1 →	+0.391	+1.917	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,562 associations by consensus.

RN7SL83P by ATXN3L expression — SARC

Explore this box plot interactively →