ATXN1-AS1

Across TCGA patient cohorts, ATXN1-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATXN1-AS1-associated GO terms across cancer lineages are Positive regulation of autophagy, Regulation of macroautophagy, and Obsolete selective autophagy. Each is linked with ATXN1-AS1 in more than 32 cancer types. Because this analysis shows association rather than direction, both ATXN1-AS1-to-partner and partner-to-ATXN1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by ATXN1-AS1-low versus ATXN1-AS1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN1-AS1→partner) and Y-score (partner→ATXN1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Positive regulation of autophagy →	+0.055	+0.996	<.001	<.001	3	33
THYM	Regulation of macroautophagy →	+0.057	+0.991	<.001	<.001	3	33
THYM	Obsolete selective autophagy →	+0.068	+1.219	<.001	<.001	3	33
UCS	Endosomal transport →	+0.048	+1.349	<.001	<.001	3	32
THYM	Cytosolic transport →	+0.049	+1.049	<.001	<.001	3	32
THYM	Cellular response to insulin stimulus →	+0.062	+1.134	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

Positive regulation of autophagy by ATXN1-AS1 expression — THYM

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