ATXN1-AS1

Across TCGA pan-cancer cohorts, ATXN1-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ATXN1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATXN1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATXN1-AS1 is over-expressed in tumor, although a few such as THCA and BLCA show the opposite, repressed pattern.

COAD, THCA, and HNSC are the cancer types where ATXN1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATXN1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+0.883	<.001	9	view →
THCA	All	II,III,IV	−0.868	<.001	8	view →
HNSC	Male	III,IV	+0.638	.010	7	view →
BLCA	All	IV	−0.954	.012	5	view →
STAD	Female	III,IV	−0.735	.001	3	view →
LUAD	All	All	−0.319	.005	3	view →
LUSC	All	III,IV	−0.845	.011	2	view →
KIRP	All	IV	+0.559	.034	2	view →
PRAD	All	All	−0.379	.014	2	view →
KIRP	All	All	−0.344	.015	2	view →
LIHC	All	All	+0.310	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

ATXN1-AS1–COAD

Open the COAD breakdown →