ATXN1-AS1

Across TCGA pan-cancer cohorts, ATXN1-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ATXN1-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ATXN1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ATXN1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, SKCM, and UVM are the cancer types where ATXN1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.791	0.591	<.001	79	view →
SKCM	OS	Tertile	All	0.396	0.263	<.001	77	view →
UVM	DFS	Median	All	0.254	0.668	.003	73	view →
ACC	DFS	Median	All	0.374	0.789	<.001	50	view →
THCA	OS	Median	IV	0.584	0.939	.009	35	view →
READ	OS	Median	II,III,IV	0.826	0.424	.008	32	view →
UCS	DFS	Median	IV	0.952	0.367	.001	24	view →
KIRC	OS	Median	All	0.845	0.765	.004	21	view →
LGG	OS	Median	All	0.744	0.897	.002	20	view →
HNSC	DFS	Median	IV	0.724	0.555	.001	17	view →
PAAD	OS	Median	II,III,IV	0.642	0.454	.014	16	view →
BLCA	OS	Median	All	0.348	0.533	.013	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ATXN1-AS1–LUAD (OS)

Open the LUAD breakdown →