ATP6V1H

Across TCGA patient cohorts, ATP6V1H protein abundance is significantly associated with the RNA expression of many other genes, with 12,224 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP6V1H-associated genes across cancer lineages are ATP6V1B2, SLC31A2, and ATP6V0D2. Each is linked with ATP6V1H in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP6V1H-to-partner and partner-to-ATP6V1H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1H versus ATP6V1B2 in COAD, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1H→partner) and Y-score (partner→ATP6V1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATP6V1B2 →	+0.470	+0.179	<.001	<.001	3	7
GBM	SLC31A2 →	+0.718	+0.482	<.001	<.001	3	4
CCRCC	ATP6V0D2 →	+0.874	+0.201	<.001	.001	3	4
COAD	CTSB →	+0.825	+0.237	<.001	.002	3	4
COAD	R3HCC1 →	+0.609	+0.222	<.001	<.001	3	4
GBM	FIG4 →	+0.339	+0.363	.005	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,224 associations by consensus.

ATP6V1H vs ATP6V1B2 — COAD

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