ATP6V1H

Across TCGA pan-cancer cohorts, ATP6V1H RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ATP6V1H’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ATP6V1H RNA is repressed in tumor relative to normal tissue. In most cancer types ATP6V1H is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and HNSC are the cancer types where ATP6V1H tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V1H RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−1.085	<.001	11	view →
THCA	All	IV	−0.997	<.001	11	view →
HNSC	All	III,IV	+0.507	<.001	11	view →
LIHC	Male	II,III,IV	+1.384	<.001	9	view →
KIRP	Male	All	−0.738	<.001	7	view →
BRCA	All	III,IV	+0.646	<.001	6	view →
COAD	Female	II,III,IV	+0.467	<.001	6	view →
CHOL	All	All	+1.754	<.001	5	view →
UCEC	All	III,IV	+0.496	.010	4	view →
STAD	Male	II,III,IV	+0.570	.047	2	view →
READ	Male	All	+0.526	.008	2	view →
LUAD	Female	II,III,IV	−0.312	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ATP6V1H–KIRC

Open the KIRC breakdown →