ATP6V1H

Across TCGA patient cohorts, ATP6V1H mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V1H-associated genes across cancer lineages are Tuberin, Snail, and c-Kit. Each is linked with ATP6V1H in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1H-to-partner and partner-to-ATP6V1H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin grouped by ATP6V1H-low versus ATP6V1H-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1H→partner) and Y-score (partner→ATP6V1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Tuberin →	+0.389	+3.000	.037	.036	3	2
UCEC	Snail →	-0.215	-2.502	.038	.001	3	2
UCEC	c-Kit →	-0.172	-1.459	.022	.012	3	2
UCEC	Cyclin-B1 →	+0.478	+1.807	.008	.025	3	2
UCEC	14-3-3_beta →	-0.076	-1.651	.019	.019	3	1
UCEC	EGFR_pY1068 →	-0.240	-1.906	.003	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Tuberin by ATP6V1H expression — SKCM

Explore this box plot interactively →