ATP6V1H

Across TCGA cell cohorts, ATP6V1H RNA expression is significantly associated with the go_rna of many other GO terms, with 3,260 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ATP6V1H-associated GO terms across cancer lineages are Golgi lumen acidification, Synaptic vesicle lumen acidification, and Endosomal lumen acidification. Each is linked with ATP6V1H in more than 16 cancer types. Because this analysis shows association rather than direction, both ATP6V1H-to-partner and partner-to-ATP6V1H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi lumen acidification grouped by ATP6V1H-low versus ATP6V1H-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1H→partner) and Y-score (partner→ATP6V1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Golgi lumen acidification →	+0.136	+1.130	.001	<.001	3	17
SOFT_TISSUE	Synaptic vesicle lumen acidification →	+0.147	+0.821	<.001	<.001	3	17
LIVER	Endosomal lumen acidification →	+0.147	+1.005	.005	.009	3	15
LUNG_SCLC	Synaptic vesicle maturation →	+0.138	+0.827	<.001	<.001	3	13
LUNG_SCLC	Negative regulation of protein localization to centrosome →	+0.138	+0.773	.001	<.001	3	12
SOFT_TISSUE	Vacuolar acidification →	+0.095	+0.754	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,260 associations by consensus.

Golgi lumen acidification by ATP6V1H expression — LIVER

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