ATP6V1H

Across TCGA cell cohorts, ATP6V1H mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6V1H-associated genes across cancer lineages are PRND, GML, and CCKAR. Each is linked with ATP6V1H in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V1H-to-partner and partner-to-ATP6V1H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRND grouped by ATP6V1H-low versus ATP6V1H-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1H→partner) and Y-score (partner→ATP6V1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRND →	+0.011	+4.874	<.001	.002	3	2
BLOOD_Leukemia	GML →	+0.080	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CCKAR →	+0.043	+4.409	<.001	.005	3	1
BLOOD_Leukemia	TACR3 →	+0.043	+5.060	<.001	.001	3	1
BLOOD_Leukemia	NKX2-6 →	+0.489	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	OR1G1 →	+0.083	+4.705	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

PRND by ATP6V1H expression — BLOOD_Leukemia

Explore this box plot interactively →