ATP6V1C2

Across TCGA patient cohorts, ATP6V1C2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,044 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ATP6V1C2-associated genes across cancer lineages are GRHL1, KLRB1, and HNRNPA1L2. Each is linked with ATP6V1C2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP6V1C2-to-partner and partner-to-ATP6V1C2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP6V1C2 versus GRHL1 in OV, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V1C2→partner) and Y-score (partner→ATP6V1C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GRHL1 →	+1.144	+1.497	.001	.002	3	3
BRCA	KLRB1 →	-1.721	-1.098	<.001	.001	3	2
BRCA	HNRNPA1L2 →	-0.751	-1.048	.007	.004	3	2
HNSC	CHN2-AS1 →	-0.653	-0.769	.002	.001	3	2
HNSC	ANTXRLP1 →	-0.607	-0.724	.001	.003	3	2
BRCA	MIR6719 →	-2.570	-1.259	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,044 associations by consensus.

ATP6V1C2 vs GRHL1 — OV

Explore this scatter interactively →