Across TCGA patient cohorts, ATP6V0C mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6V0C-associated genes across cancer lineages are MIR4692, FTLP5, and FAM106DP. Each is linked with ATP6V0C in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0C-to-partner and partner-to-ATP6V0C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0C→partner) and Y-score (partner→ATP6V0C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4692 →	+0.500	+4.132	<.001	.009	3	1
UCEC	FTLP5 →	+0.395	+3.598	<.001	.009	3	1
SKCM	FAM106DP →	+0.120	+5.037	<.001	.009	3	1
SKCM	OR5AQ1P →	+0.636	+5.037	<.001	.009	3	1
SKCM	RNU6-263P →	+0.833	+5.224	<.001	.007	3	1
SKCM	RNU105B →	+0.270	+5.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ATP6V0C survival (RNA) · tumor vs normal (RNA) · all ATP6V0C data types