ATP6V0A1

Across TCGA cell cohorts, ATP6V0A1 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6V0A1-associated genes across cancer lineages are GHRH, DRD3, and OR1L3. Each is linked with ATP6V0A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6V0A1-to-partner and partner-to-ATP6V0A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRH grouped by ATP6V0A1-low versus ATP6V0A1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6V0A1→partner) and Y-score (partner→ATP6V0A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GHRH →	+0.060	+4.906	<.001	.006	3	1
OESOPHAGUS	DRD3 →	+0.036	+4.906	<.001	.006	3	1
BREAST	OR1L3 →	+0.022	+5.169	<.001	.005	3	1
BREAST	OR4E1 →	+0.150	+5.781	<.001	.001	3	1
BLOOD_Leukemia	PHOX2B →	+0.017	+3.365	<.001	.005	3	1
BLOOD_Leukemia	BTBD16 →	+0.084	+3.959	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

GHRH by ATP6V0A1 expression — OESOPHAGUS

Explore this box plot interactively →