ATP6V0A1

Across TCGA pan-cancer cohorts, ATP6V0A1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ATP6V0A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ATP6V0A1 RNA is repressed in tumor relative to normal tissue. In most cancer types ATP6V0A1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KICH, LIHC, and HNSC are the cancer types where ATP6V0A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP6V0A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−1.642	<.001	11	view →
LIHC	Male	III,IV	+1.278	<.001	9	view →
HNSC	All	II,III,IV	+0.319	<.001	7	view →
LUSC	Female	All	−0.612	<.001	6	view →
KIRP	All	All	+0.579	<.001	6	view →
LUAD	Male	All	−0.533	<.001	5	view →
KIRC	All	All	+0.272	.002	4	view →
BLCA	Male	All	−0.339	.014	3	view →
THCA	Male	III,IV	−0.317	.007	3	view →
CHOL	Male	All	+1.424	<.001	2	view →
UCEC	All	All	−0.474	.005	2	view →
BRCA	Female	All	−0.134	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ATP6V0A1–KICH

Open the KICH breakdown →