ATP6AP1L

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP6AP1L mutation is significantly associated with the RNA expression of many other genes, with 1,469 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6AP1L-associated genes across cancer lineages are E2F6P1, PLTP, and CST3. Each is linked with ATP6AP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6AP1L-to-partner and partner-to-ATP6AP1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6AP1L→partner) and Y-score (partner→ATP6AP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCME2F6P1 →+0.029+3.594<.001.00332
UCECPLTP →-0.928-3.898.001<.00132
UCECCST3 →-0.636-4.000.001<.00132
UCECCSTF2 →+0.485+2.673.001<.00132
UCECEIF3J →+0.597+2.662<.001<.00132
UCECOIP5 →+0.859+3.923<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,469 associations by consensus.

Exploration