Across TCGA pan-cancer cohorts, ATP6AP1L RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ATP6AP1L data layer compared with 4 for mutation status.
The strongest signal is observed in kidney chromophobe (KICH), where higher ATP6AP1L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ATP6AP1L expression acts as an unfavorable survival marker, although some lineages such as SKCM and READ show a favorable association.
KICH, KIRC, and SKCM are the cancer types where ATP6AP1L RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.